S-Adenosyl L-Methionine Disulfate Tosylate (SAMe DTS) is a stabilized salt form of SAMe, an essential biological methyl donor involved in transmethylation, transsulfuration, and aminopropylation pathways.
The disulfate tosylate form offers enhanced stability compared to free SAMe, making it suitable for pharmaceutical and nutraceutical formulations requiring controlled stability and bioavailability.
1. PRODUCT IDENTIFICATION
| Common Name | SAMe Disulfate Tosylate |
| Chemical Name | (3-Amino-3-carboxypropyl)-(5′-deoxyadenosyl)-sulfonium sulfate p-toluenesulfonate |
| Synonyms | SAMe DTS, Ademetionine Disulfate Tosylate |
| CAS No. | 97540-22-2 |
| Molecular Formula | C₁₅H₂₂N₆O₅S⁺ · ½H₂SO₄ · p-CH₃C₆H₄SO₃H |
| Molecular Weight | ~766.8 g/mol (approx.) |
2. PRODUCT DESCRIPTION
SAMe Disulfate Tosylate serves as a highly bioavailable methyl donor and supports liver function, joint health, neurotransmitter synthesis, and cellular metabolism.
3. GRADE
- Pharmaceutical Grade (USP / IH compliant where applicable)
- Nutraceutical / Food Grade
(Grade supplied as per customer specification.)
4. DOSAGE FORMS / AVAILABILITY
- Off-white to white crystalline powder
- Granular / lyophilized form (on request)
5. TECHNICAL SPECIFICATIONS
| Description | White to off-white powder |
| Identification | Conforms |
| Assay (SAMe content) | ≥ 95.0% |
| pH (1% solution) | 1.0 – 5.0 |
| Loss on Drying | ≤ 3.0% |
(Specifications may vary based on pharmacopeial or customer requirements.)
6. FUNCTIONAL PROPERTIES
- High chemical stability compared to free SAMe
- Highly bioavailable methyl donor
- Freely soluble in water
- Hygroscopic; requires controlled handling
7. APPLICATIONS
Nutraceuticals- Liver health formulations
- Joint health supplements
- Mood & cognitive support products
- Hepatoprotective formulations
- Antidepressant and osteoarthritis therapies
Clinical Nutrition
- Methylation and metabolic support
8. REGULATORY & COMPLIANCE
- Manufactured in GMP-certified facilities
- Complies with applicable USP / IH standards
- Non-GMO
- BSE/TSE Free
- Allergen Free
Documents Available:
- Certificate of Analysis (CoA)
- MSDS / SDS
- Stability data
- Manufacturing flow chart (on request)
9. PACKAGING
- Primary: Double LDPE bags
- Secondary: 25 kg HDPE drums
- Custom packaging available upon request
10. STORAGE & SHELF LIFE
- Store at 2–8°C, protected from light and moisture
- Keep container tightly closed
- Shelf Life: 24 months under recommended storage conditions
11. SAFETY INFORMATION
- Avoid exposure to heat and humidity
- Refer to MSDS for safe handling and transport
12. COMMERCIAL INFORMATION
- MOQ: As per grade and packaging
- Lead Time: 7 Days
- Supply Capability: Bulk and contract supply
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