Trypsin–Chymotrypsin (6:1) is a synergistic proteolytic enzyme combination formulated in a fixed 6:1 ratio to enhance protein degradation, reduce inflammatory exudates, and support faster tissue recovery.
It is widely used in pharmaceutical formulations for post-surgical, orthopedic, dental, ENT, and traumatic conditions due to its anti-inflammatory, anti-edematous, and fibrinolytic properties.
1. PRODUCT IDENTIFICATION
| Enzyme Composition | Trypsin : Chymotrypsin (6 : 1) |
| Enzyme Class | Proteolytic enzymes (Serine proteases) |
| Source | Microbial Fermentation |
| EC Numbers |
Trypsin: EC 3.4.21.4 Chymotrypsin: EC 3.4.21.1 |
2. PRODUCT DESCRIPTION
Trypsin–Chymotrypsin (6:1) provides enhanced proteolytic activity through its optimized enzyme ratio, helping reduce inflammation, edema, and tissue damage while promoting faster healing in traumatic and post-operative conditions.
3. GRADE
- Pharmaceutical Grade (In-house specification)
- Nutraceutical Grade
(Grade supplied as per customer requirement.)
4. AVAILABLE FORM
A white to almost white powder
5. TECHNICAL SPECIFICATIONS
| Description | A white to almost white powder |
| Identification | Conforms |
| Enzyme Ratio | Trypsin : Chymotrypsin = 6 : 1 |
| Trypsin Activity | ≥ 2400 Units/mg |
| Chymotrypsin Activity | ≥ 400 Units/mg |
| Loss on Drying | ≤ 5.0% |
(Enzyme activities can be adjusted or customized based on formulation needs.)
6. ENZYMATIC PROPERTIES
- Optimal pH: 7.0 – 8.5
- Optimal Temperature: 35°C – 40°C
7. APPLICATIONS
Pharmaceuticals- Anti-inflammatory and anti-edematous formulations
- Post-operative and post-traumatic recovery products
- Orthopedic, dental, and ENT preparations
Nutraceuticals
- Joint health and recovery supplements
- Sports injury and inflammation support
8. REGULATORY & COMPLIANCE
- Manufactured in GMP-certified facilities
- Complies with IH (In-house standards)
- BSE/TSE Controlled (with documentation)
- Allergen Information: Porcine-derived enzyme
Documents Available:
- Certificate of Analysis (CoA)
- MSDS / SDS
- Stability data
- TSE/BSE declaration
9. PACKAGING
- 5 kg / 10 kg / 25 kg HDPE drum with double LDPE liner
- Custom packaging available on request
10. STORAGE & SHELF LIFE
- Store in a cool, dry place, protected from heat and moisture
- Keep container tightly closed
- Shelf Life: 24–36 months under recommended storage conditions
11. SAFETY INFORMATION
- For industrial and formulation use only
- Avoid inhalation of enzyme dust
- Use appropriate PPE
- Refer to MSDS for detailed handling and safety instructions
12. COMMERCIAL INFORMATION
- MOQ: As per enzyme activity and packaging
- Lead Time: 7 Days
- Supply Capability: Bulk, contract, and export supply
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